Opioids cross the placenta and could produce respiratory depression and psycho-physiologic consequences in neonates. An opioid antagonist, like naloxone, have to be obtainable for reversal of opioid-induced respiratory despair within the neonate. OXYCONTIN will not be advisable to be used in Girls instantly ahead of labor, when usage of shorter-performing analgesics or other analgesic techniques are more correct.

Make certain you know the way to take oxycodone and what other drugs it is best to avoid having with it. See also Drug Interactions section. Get health-related help immediately if any of these really significant side effects take place: slow/shallow respiration, uncommon lightheadedness, serious drowsiness/dizziness, trouble waking up.

Start off typing to retrieve research strategies. When tips are available expend and down arrows to evaluate and ENTER to select. Proceed typing to refine.

Drug withdrawal syndrome Previous to setting up remedy with any opioids, a dialogue ought to be held with sufferers To place in position a withdrawal approach for ending treatment with oxycodone.

We only use high-quality, credible resources to be certain content accuracy and integrity. You could find out more regarding how we assure our written content is correct and present by examining our editorial policy.

If an opioid analgesic is initiated within a patient already getting a benzodiazepine or other CNS depressant, prescribe a lower Preliminary dose in the opioid analgesic, and titrate determined by clinical response. Inform people and caregivers of the potential interaction and teach them to the signs and symptoms of respiratory depression (such as sedation).

A Health care professional need to be consulted in advance of taking any drug, changing any diet program or commencing or discontinuing any study course of therapy.

To minimize the prospect of choking or acquiring problems swallowing the tablet, get only one a tablet at a time Should your dose is for more than one tablet. Will not pre-soak, lick, or moist the tablet before placing it within your mouth. You'll want to consume adequate drinking water with each tablet to swallow it entirely.

Suggest equally clients and caregivers regarding the dangers of respiratory despair and sedation when OXYCONTIN is made use of with benzodiazepines or other CNS depressants (including alcohol and illicit medication). Recommend clients not to push or function large machinery right up until the consequences of concomitant use on the benzodiazepine or other CNS depressant have already been determined.

To lessen your threat, your medical professional must have you take the smallest dose of oxycodone that actually works, and take it to the shortest doable time. See also How you can Use area To find out more about habit.

Since the utilization of OXYCONTIN exposes patients as well as other users to the dangers of opioid dependancy, abuse, and misuse, which can result in overdose and death, check here assess Every single affected individual's chance before prescribing and reassess all patients often for the event of these behaviors and conditions [see Warnings and Precautions (five.1)].

For the reason that these reactions are claimed voluntarily from a inhabitants of unsure dimensions, It's not often probable to reliably estimate their frequency or set up a causal romance to drug exposure.

OXYCONTIN may possibly result in significant hypotension, including orthostatic hypotension and syncope in ambulatory individuals. There is certainly an increased risk in people whose capacity to take care of blood pressure level has previously been compromised by a lowered blood quantity or concurrent administration of specified CNS depressant medications (e.

Before taking oxycodone, explain to your health care provider or pharmacist If you're allergic to it; or to other opioid discomfort relievers (for example oxymorphone); or if you have any other allergic reactions.